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Home Internal medicine QUIZ: Dyspnoea *solved*

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QUIZ: Dyspnoea *solved* PDF Print E-mail
Author: aSia
User Rating: / 3
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Sunday, 13 December 2009 13:45

Case description: 62-years old female enters the A&E. The reason of her visit is dyspnoea, which occurred this morning, when the patient went outdoor to open the poultry-house (this wasn't a big effort, but a patients everyday activity, which she used perform without any problems). The patient describes her complaint as shortness of breath, and clogged feeling. She has been feeling weak for a long time now, her legs hurt, but 2 weeks ago, the weakness slightly increased and the shortness of breath began to occur.
History: breast cancer, mastectomy 3 years ago. Patient is under constant care of an oncologist.

Abnormalities in physical examination:
Tachycardia (120/min)
crural varices

QUIZ questions:
What procedures do you order? What is the diagnosis and the treatment?


 

Comments  

 
0 #1 MMader 2009-12-13 14:14
At the moment it isn't looking specific, so we should do the basic tests:
ECG
Heart USG
morphology

Patient has dyspnoea, but in the description of physical examination I don't see any auscultation and percussion abnormalities.
I'll wait for result of basic tests, because if we have nothing, guessing doesn't make sense...
But if I was House MD, I'd think about psittacosis.
 
 
0 #2 aSia 2009-12-13 17:49
Morphology:
RBC - 4,3 M/uL; HBG - 11 g/dl; MCV - 83 fl; MCH - 28 pg; MCHC - 34 g/dl; WBC - 5,2 K/uL; PLT - 480 K/uL

ECG:
sinus tachycardia

We can make heart USG tomorrow in our hospital.

The patient was asked about a contact with a parrot - denies ;-) except them chickens... :-)
 
 
0 #3 silver 2009-12-13 18:27
I would do a bronchofiberosc opy and I'd send culture samples, by the way watching if it's all OK with lungs.
 
 
0 #4 silver 2009-12-13 18:29
and also gasometry!
 
 
0 #5 silver 2009-12-13 18:32
and electrolytes :-)
 
 
0 #6 MMader 2009-12-13 18:32
I forgot about chest X-ray - it can tell us something.
 
 
0 #7 Anna Kamińska 2009-12-13 19:41
X-ray would surely be appropriate + d-dimers. I suspect an pulmonary embolism (PE) (risk factors: neoplasma and crural varices). Because of NPL I wonder about chronic DC. Of course it can be a casual thrombosis. What do her legs look like?
 
 
0 #8 aSia 2009-12-13 22:15
Gasometry:
pH 7,39; pO2 68mmHg; pCO2 41 mmHg; HCO3 24 mmol/l; SpO2 91%; BE 1,5 mEq/l

Electrolytes:
Na 139 mEq/l; K 3,9 mEq/l; Cl 101 mEq/l

Chest X-ray didn't reveal any abnormalities.

D-dimers - positive
Crural varices, slight oedema of right leg + hyperpigmentati ons and sclerosis of right ankle.

There aren't any indications of bronchofiberosc opy.
 
 
0 #9 diabeł 2009-12-14 20:49
PE makes sense (cancer + crural varices). In my opinion the progression is too slow for PE, but let's follow this clue. I'd ask if she wasn't immobilized for some time in the past, for example due to recently past diseases or trauma, which caused a longer stay in bed. I thought about echocardiograph y, but since ECG is clean I give it up. If CT is available - let's do it but at first I'd like to have some info from the auscultation results and how much time has passed since the symptoms occurred?
 
 
0 #10 Anna Kamińska 2009-12-14 21:35
A problem with PE is as follows:
If big embolus occurs, acute symptoms direct us to appropriate diagnosis, but the emboli may be small and smaller vessels are obturated. Then it's possible to mistake it for, let's say, pneumonia
 
 
0 #11 aSia 2009-12-14 22:24
The patient came to hospital at 4 pm, and the symptoms occurred about 8 am.
There weren't any abnormalities in auscultation .
Angio-CT was performed - a embolus in peripheral arteries was visualised. So dr Fisch was right - diagnosis is pulmonary embolism (non-massive). And exactly as dr Fish has written, symptoms don't have to occur suddenly.
After few hours, the patient's son brought a documentation. Earlier lab-tests' results, which the patient made in oncologist control and GP control, show increased d-dimers concentration in blood. Perhaps we have to deal with chronic pulmonary embolia. That condition can lead to right-heart overload and developing a pulmonary hypertension.

What is the treatment?
 
 
0 #12 Mateusz Palczewski 2009-12-21 14:06
We have to implement anticoagulants (small-molerular heparin subcutaneusly or non-fractionated i.v.), thrombolytics (tPA, streptokinase). Additionally we should use oxygen therapy, catecholamines (dopamine, dobuthamine) and carefully we could give 0,9% solution NaCl (no more than 1l).
 
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