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Home Outpatients clinic QUIZ: Atypical pneumonia? *solved*

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QUIZ: Atypical pneumonia? *solved* PDF Print E-mail
Author: G.J.
User Rating: / 3
PoorBest 
Saturday, 31 October 2009 00:15

Case description:

48 years old man came to a GP to have a check-up after macrolides therapy for a dry cough which he had for two weeks. The cough was gone but he started feeling his muscles weakening in lower limbs, cramps and began to have a double vision. He is still generaly weak.

Auscultation: sharpened alveolar murmurs, single additional contractions.

ECG: single supraventricular contractions

QUIZ questions: What other tests should be done to eventually verify differential diagnoses? What's with patient?

 

 

Comments  

 
0 #1 kisia 2009-10-31 01:45
macrolides - the doctor could suggest atypical pneumonia... mycoplasma. Maybe we should make a morphology with blood smear and echo?
I would ask for HIV tests as well.
 
 
0 #2 Gonzo 2009-10-31 02:06
Chest X-ray and BAL in case of any abnormalities.
 
 
0 #3 G.J. 2009-10-31 09:17
morphology: slight neutrophilia with left-shifted differential smear
heart echo: mitral insufficiency - hemodynamicly insignificant
HIV-1, HIV-2 - negative
X-ray: status after VI rib fracture
Cultures: negative (during antibiotics therapy?)
 
 
0 #4 aniamos 2009-10-31 19:59
What about electrolytes?
I suggest:
- antibodies versus Mycoplasma antigens in IgM and IgG class
- neurological examination - deep reflexes
- cerebrospinal fluid leak test, EMG eventually to exclude Guillain-Barry syndrome
 
 
0 #5 G.J. 2009-11-01 11:28
Electrolytes in norm,
Antibodies in high level, IgG especially

In neurological examination: symmetrical weakness of deep reflexes of lower limbs, sens disorder, weakness of oculomotor muscles

EMG: slowed down conduction, elongated F wave latency
 
 
0 #6 aniamos 2009-11-01 12:57
Heart arrythmias, neurological disorders make me thinking about Guillain-Barry syndrome. The diagnosis would be confirmed if there would be protein-cellular split (proteins > 2g and proper cells count). It should be differentially diagnosed with Lyme disease and MG (miastenia gravis).

treatment: immunoglobulins and plasmaferesis should be considered, macrolides should be taken till the end of cycle.
monitoring: pressure, EKG, EMG, neurological examinations
 
 
0 #7 G.J. 2009-11-01 18:33
Bravo - I'm impressed:-) What other diseases could give similar symptoms to Guillain-Barre syndrome?
 
 
0 #8 MMader 2009-11-11 13:34
SM
 
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